Although once common in writing and speech, by now many of us have realized that “irregardless” is incorrect (The prefix IR and the suffix LESS are both negatives). But there are other incorrect versions of the word “Regardless” that still find their way into our vocabulary on a regular basis. The most common, “in regards to”, is typically found in business emails or longer pieces of content (such as case studies or essays) in an attempt to sound more formal.
The proper way to use the word in this case is “in regard to”, with no “s”. “Regards”, plural, is a word used to indicate kindly feelings to or about a person, and is used in closing (example, at the end of an email). When using the term to introduce a topic, we use the singular form. “Concerning” would be synonymous with “in regard to”.
Another form we tend to see, “regarding to”, likely comes from having a similar structure to “according to” or “due to” and has managed to find it’s way into our language – but it’s just flat out wrong and there isn’t a proper way to use “Regarding” in this way.
All that being said, the simplest and least confusing way of phrasing it is just “regarding”. There is no need to complicate your writing, and in fact the point will be made better when you keep it short, sweet, and simple.